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09 February 2024

A Study Into The Association Between Psoriasis And Gene KLK7

Psoriasis is often described as an auto-immune disease or immune-mediated condition. The relationship between genetic factors and psoriasis is not entirely clear.

A recent study conducted in the USA sheds light on a promising link between a specific gene - KLK7 and the response to treatments.

The study took a unique approach and harnessed response data through surveys from over 1,900 psoriasis patients. This method allowed for a broader participant pool and reduced the need for frequent follow-up visits.

Various treatment options, including oral medications, topical agents, injections and phototherapy were analysed to understand individual responses.

The focal point of this discovery is the gene KLK7, which appears to play a key role in how individuals respond to treatment.

Researchers found that inhibiting KLK7 resulted in significantly improved treatment outcomes.

This discovery opens doors to more effective and tailored psoriasis treatments based on an individual’s genetic makeup.

The journey toward personalised psoriasis care looks positive and there are undoubtedly promising times ahead.

For more details, read a lay summary of the article on the BJD website.

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